Assessment of recovery levels of organophosphorus toxic substances conversion products from building materials by high-performance liquid chromatography with tandem mass-selective detection
Abstract
A list of substances (markers) has been established for the retrospective determination of the fact of contamination of various materials with organophosphorus toxic substances. The "long-lived" markers of contamination include: O-isobutyl-S-(2-diethylaminoethyl) methylphosphonothioate (VR) and 11 products of the conversion of organophosphorus toxic substances: diisopropylmethylphosphonate (diPrMP), isopropyl-isobutyl methylphosphonate (iPr-iBMP), isobutyl-pinacolylmethylphosphonate (iBPMP), dipinacolylmethylphosphonate (dPMP), diisobutylmethylphosphonate (diBMP), isobutyl methylphosphonic acid (iBMPA), bis(2-diethyl-aminoethyl) disulfide (DEAEdiS); S-2-(diethylaminoethyl) methylphosphonothioate (DEMP); O-isopropyl methylphosphonic acid (iPrMPA), O-isobutyl methylphosphonic acid (iBMPA), O-pinacolylmethylphosphonic acid (PMPA), methylphosphonic acid (MPA). A method for detecting and identifying these markers in building materials by high-performance liquid chromatography with tandem mass-selective detection has been developed. In the case of detection of highly toxic VR and S-2-(diethylaminoethyl) methylphosphonothioate, their quantitative determination is provided according to the certified method of FR.1.31.2020.36539.
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