Measurement method of agidol-40, acetophenone, vulkacite-P-extra N, sulphenamide C mass concentrations in aqueous matrices

Keywords: : mass concentration, high-performance liquid chromatography, UV detection

Abstract

In the chemical industry various substances are used in the production of materials and products, acting as monomers, solvents, catalysts, stabilizers, antioxidants, etc. In particular, in the production of polymeric materials agidol-40 is widely used as an antioxidant, acetophenone as a solvent, vulkacit-P-extra H and sulfenamide C as vulcanizers. These substances can migrate from materials and products into water matrices. There is no method of their joint determination in the world. For the first time a method for the simultaneous determination of agidol-40, acetophenone, vulkacite-P-extra H, and sulfenamide C in aqueous matrices has been developed. The determination is carried out by high-performance liquid chromatography (HPLC) with detection at 240 nm and absolute calibration method. Preliminarily the substances are extracted twice from 50 cm3 of an aqueous extract with dichloromethane, 30 cm3 each, the resulting extract is concentrated under vacuum, the dry residue is dissolved in acetonitrile (1 cm3). A Nucleodur C18 Pyramid (Macherey-Nagel) column (250 mm × 3.0 mm, grain size 5.0 μm; thermostat temperature 25°С) is used as a stationary phase. A mixture of water with acetonitrile and 2-propanol in a ratio of 4:74:22 (v : v) is used as a mobile phase. The limit of quantitative detection of vulcacit in water extracts from consumer goods is 0.31 mg/dm3, sulphenamide С – 0.08 mg/dm3, agidol-40 – 0.13 mg/dm3, acetophenone – 0.02 mg/dm3.

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Published
2022-06-06
How to Cite
KuzovkovaА. A., Turko, M. S., & Krymskaya, T. P. (2022). Measurement method of agidol-40, acetophenone, vulkacite-P-extra N, sulphenamide C mass concentrations in aqueous matrices. Chemical Safety Science, 6(1), 173 - 189. https://doi.org/10.25514/CHS.2022.1.21011
Section
Indication and identification of hazardous substances