Modern approaches to the development of efficient systems of SiO2-CaO bioglasses doped with iron(III) and zinc(II) compounds
Abstract
Abstract – The results of a comparative assessment of the synthesis conditions, physicochemical characteristics, and bioactivity of glassy systems of the form 60SiO2–(40–x)CaO–xFe2O3 (x = 0, 1, 3, 5% mol.) and 70SiO2–(30–x)CaO– xZnO (x = 1, 3, 5% mol.). It has been established that the sintering temperature for obtaining zinc-containing powders is 700°C; for iron-containing powders – 750°C. It was found that the content of Fe2O3 and ZnO affects the amorphous nature of glassy iron- and zinc-containing systems. Iron-containing systems are amorphous when Fe2O3 is doped in an amount x = 0 and 1 mol.%; zinc-containing - with ZnO doping in the amount of x = 1, 3, 5% mol. It has been shown that iron- and zinc-containing systems are bioglasses (BG) and their bioactivity is confirmed by the presence of peaks of mineral layers of hydroxyapatite at 2θ = 26° (002), 32° (211) in the X-ray diffraction spectra after keeping the samples in the SBF solution. With an increase in the content of Fe2O3 or ZnO from 0÷1% mol. to 5% mol., the bioactivity decreases, which is confirmed by the decrease or disappearance of one of the peaks of hydroxyapatite in the systems 60Si37Ca3Fe, 70Si35Ca5Zn. The most active formation of hydroxyapatite layers is observed for 60Si39Ca1Fe, 70Si39Ca1Zn. The results of studies of magnetic, thermal, and textural properties show that Fe (III) and Zn (II) ions are vitreous network modifiers, replacing calcium and silicon ions in it. It was found that the addition of Fe (III) ions induces the magnetic properties of systems while maintaining their bioactivity. The magnetic properties increase with increasing Fe2O3 content. An increase in the content of ZnO from 1 to 5% mol. in systems causes a decrease in the phase transition temperature and causes a decrease in porosity. The addition of ions of the above elements gives BG useful properties, while BG dissolves in the body without a trace, without forming toxic chemical compounds.
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