Toxicity Behavior of Hydrozol Based on Silver Nanoparticles and Stabilized by Pectin
Abstract
A series of experimental studies was been performed on animal models for evaluating acute toxicity of silver nanoparticle-based hydrosol stabilized by pectin (pectin-Ag nanocomposite), which had been previously synthesized and purified in accordance with green chemistry principles. The parameters of acute toxicity were determined for multiple routes of nanocomposite administration (i.e. intragastric, intraperitoneal, and inhalation). The results obtained made it possible to classify the pectin-Ag nanocomposite for hazard degree. In addition, species sensitivity was characterized, and skin-irritating, resorptive and irritative effect was studied.
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